7DSNA

Overall structure of the lat1-4f2hc bound with jx-119
Total Genus 111
50100150200250300350400450020406080100
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
471
structure length
471
Chain Sequence
KFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAGNLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWFSTQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLLLTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAALPGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQNERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
50100150200250300350400450400300200100
020406080100Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYS7 (376-380)TIV3 (176-179)TIV1 (161-164)TIV2 (173-176)AH2 (179-207)S4 (276-281)TI1 (218-221)TIV6 (237-240)AH3 (242-246)TI3 (220-223)S1 (224-228)AH4 (248-255)TI4 (230-233)TVIII1 (228-231)S2 (257-262)S3 (266-268)TI7 (272-275)S5 (304-308)3H1 (283-285)TI10 (312-315)AH5 (288-300)TIV7 (310-313)TVIII2 (315-318)S6 (345-349)TIV9 (350-353)TI12 (351-354)AH7 (357-371)TI19 (443-446)S8 (400-402)TIV11 (393-396)AH8 (386-393)TIV13 (407-410)TI15 (405-408)AH9 (413-427)TI16 (406-409)AH10 (450-459)O1 (461-463)TIV14 (427-430)S9 (432-434)S10 (463-468)TIV15 (437-440)TI17 (441-444)TIV12 (396-399)AH1 (167-173)TIV10 (354-357)TVIII3 (394-397)TI14 (404-407)AH6 (324-341)TI13 (372-375)Updating...
connected with : NaN
molecule tags Membrane protein
source organism Homo sapiens
publication title Mechanism of substrate transport and inhibition of the human heteromeric LAT1-4F2hc amino acid transporters
rcsb
molecule keywords 4F2 cell-surface antigen heavy chain
total genus 111
structure length 471
sequence length 471
ec nomenclature
pdb deposition date 2020-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00128 Alpha-amylase Alpha amylase, catalytic domain
A PF16028 SLC3A2_N Solute carrier family 3 member 2 N-terminus
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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