7EAXA

Crystal complex of p53-v272m and antimony ion
Total Genus 45

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
194
structure length
194
Chain Sequence
SVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEMRVCACPGRDRRTEEENL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYS3 (132-135)S2 (124-127)TVIII1 (122-125)S4 (139-147)S5 (156-163)AH1 (177-181)TVIII2 (147-150)TII2 (152-155)TI4 (190-193)TII1 (136-139)TI2 (119-122)TI1 (105-108)S1 (109-113)TI3 (168-171)TIV1 (186-189)3H2 (166-168)Updating...
connected with : NaN
molecule tags Antitumor protein
source organism Homo sapiens
publication title Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations.
pubmed doi rcsb
molecule keywords Cellular tumor antigen p53
total genus 45
structure length 194
sequence length 194
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2021-03-08
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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