7F58B

Cryo-em structure of thiq-mc4r-gs_nb35 complex
Total Genus 94

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
338
structure length
338
Chain Sequence
ELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
AH1 (3-25)TI15 (254-257)3H1 (30-32)TIV2 (32-35)S24 (293-298)TI19 (298-301)TI1 (33-36)TI18 (279-282)EMPTYS25 (303-309)S1 (47-51)S28 (335-339)TI21 (331-334)TI4 (84-87)TI20 (321-324)TI3 (64-67)S4 (78-83)TIV3 (66-69)S3 (69-74)S6 (100-105)TIV4 (74-77)S5 (89-94)S9 (134-140)TVIII1 (95-98)O1 (98-100)S7 (111-116)TI5 (106-109)TI6 (116-119)S8 (120-125)S10 (146-153)S14 (187-192)S12 (165-170)TI8 (153-156)S11 (156-161)S13 (175-180)TI9 (161-164)S15 (198-203)3H2 (171-173)S18 (229-234)TI10 (193-196)S16 (207-212)TIV7 (203-206)S17 (218-223)TI12 (213-216)S20 (250-254)TI13 (235-238)S21 (259-264)TI14 (245-248)TI16 (255-258)TI17 (266-269)S23 (284-289)S22 (273-278)TIV8 (289-292)S27 (327-331)S26 (317-320)S2 (58-63)TIV6 (115-118)TI7 (128-131)TVIII2 (125-128)TI11 (212-215)S19 (240-245)TIV1 (26-29)TIV5 (83-86)Updating...
connected with : NaN
molecule tags Membrane protein
source organism Homo sapiens
publication title Structural insights into ligand recognition and activation of the melanocortin-4 receptor.
pubmed doi rcsb
molecule keywords Melanocortin receptor 4
total genus 94
structure length 338
sequence length 338
ec nomenclature
pdb deposition date 2021-06-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00400 WD40 WD domain, G-beta repeat
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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