7FASA

Var2csa 3d7 ectodomain core region
Total Genus 349
20040060080010001200050100150200250300350
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
349
sequence length
1935
structure length
1229
Chain Sequence
GYYRKNIKITVNHDSGTNDPCDRPPPYGCAIILSENVFVPPRRQRCINNLEKLNVDKIRDKHAFLADVLLTARNEGERIVQNHPDTNSSNVCNALERSFADIADIIRGTDLWKGNSNLEQNLKQMFAKIRRKLREDWWNANRQKVWEVITCGARSNDLLIKRGCRKCGHYEEKVTKLDYVPQFLRWLTEWIEDFYREKQNLIDDMERHREECTCSTCKDKCKKYCECVKKWKSEWNQKNKCNCNESGIASVEQEQIKNNKNWIWKKSSGKEGGQKEYANTIGLPPRTQSLCVVCLDKGKKTQELKNIRTNSELLKEWIIAAFHEGKNLKPDDNGKKLCKALEYSFADYGDLIKGTSIWDNEYTKDLELNLQKIFGKLFRKYIEQDTSYLDELRESWWNTNKKYIWLAMKHGAGMNSTTCSSCDDIPTIDLIPQYLRFLQEWVEHFCKQRQEKVKPVIENCKSCKECKTECKNKCEVYKKFIEDCKGGDGTAGSSWVKRWDQIYKRYSKYIEDAKRNRKAGTKNCGNKCVQSDIDSFFKHLIDIGLTTPSSYLSIVLDDNICGADKAPWTTYTTYTTTEKCNTAVVVNVPSPLGNTPHGYKYACQCKIPTNEETCDDRKEYMNQWSCGSDNYELCKYNGVDVKLDDKDVTFFNLFEQWNKEIQYQIEQYMTNNCKEKCKCYSLWIEKINDQWDKQKDNYNKFQRKQIKVVSLSNFLFFSCWEEYIQYFNGDTFEFLIKKCGNDETIFSEKLNNAEKKCKENESTKIKNAIQKETELLYEYHPKGFCHAVQRSFIDYKNMILGNAWWKGIEGEMWDAVRCAITKINKKDEDQSVSWFKEWSEQFCIERLQYEKNIRDACTDKIQGDCKRKCEEYKKYISEKKQEWDKQKTKYENKYVGNKSLCHEGNDRTWSKKYIKKTLEGVYVPPRRQQLCLYELFPIIIKNNDITNAKKELLETLQIVAEREAYYLWKQYHAHNDTTYLAHKKACCAIRGSFYDLEDIIKGNDLVHDEYTKYIDSKLNEIFDSSNKNDIETKRARTDWWENEAIDPKTIRQLVWDAMQSGVRKAIDEEKPNENFPPCMGVQHIGIAKPQFIRWLEEWTNEFCEKYTKYFEDMKSNCNLSNIECKKACANYTNWLNPKRIEWNGMSNYYNKIYRKSNKESEDGKDYSMIMEPTVIDYLNKCNGEINGNYICCSCKNIGEYSEHKMKCTEVYLEHVEEQLKEIDNAIKDY
2004006008001000120012001000800600400200
050100150200250300Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYTIV4 (57-61)TIV5 (61-64)TVIII1 (62-65)TIV9 (114-117)AH1 (120-140)O1 (142-144)TIV11 (167-170)AH3 (178-226)TIV13 (230-233)AH4 (274-339)TIV14 (237-255)TVIII4 (259-262)TIV15 (427-430)TIV23 (602-605)TII1 (574-577)TIV16 (564-567)TIV18 (588-592)3H3 (572-574)TIV22 (598-601)TIV17 (575-578)TIV19 (592-596)AH5 (609-626)AH7 (667-682)TIV25 (683-686)AH16 (1132-1146)AH6 (641-658)TI6 (684-687)AH18 (1179-1306)AH8 (702-725)O2 (726-728)TIV28 (744-747)3H5 (751-753)TIV29 (781-784)AH11 (826-846)TI7 (783-786)TI8 (784-787)AH10 (801-812)TI9 (814-817)TI10 (818-821)TIV31 (821-824)AH13 (888-895)TIV32 (851-854)TIV33 (855-867)TIV34 (856-868)O3 (870-872)AH14 (962-968)TIV35 (897-900)TIV36 (899-902)TVIII6 (902-905)TIV37 (907-910)S1 (911-915)TIV38 (918-933)AH15 (1017-1116)S2 (937-941)3H6 (942-944)TVIII7 (945-948)TIV39 (951-954)TII2 (948-951)TIV40 (952-955)TIV41 (953-956)TI11 (954-957)O6 (993-995)TIV42 (998-1001)TIV7 (105-108)TVIII2 (99-102)AH2 (147-166)3H2 (342-344)AH9 (756-781)TIV26 (695-698)AH12 (873-883)O4 (884-886)TIV1 (44-48)TIV10 (116-119)TI3 (226-229)TIV43 (1146-1150)TIV6 (95-98)AH17 (1163-1170)TIV30 (797-800)TIV27 (730-743)Updating...
connected with : NaN
molecule tags Cell adhesion
source organism Plasmodium falciparum (isolate 3d7)
publication title The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum.
pubmed doi rcsb
molecule keywords Erythrocyte membrane protein 1, PfEMP1
total genus 349
structure length 1229
sequence length 1935
ec nomenclature
pdb deposition date 2021-07-07
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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