7JMSA

Structure of the hazara virus otu bound to ubiquitin
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
157
structure length
157
Chain Sequence
DFLEGITWDSVSDIQSVSNPSFTITDYFEVVRQPADGNCFYHSLAELYIPNKSDHAYRLVKNELREAAEKYFPTEPEAAATGMRLDEYLDTALRDNEWGGSLEAAMLSRHLGLTVVIWLVDGSNRVVGATRFGKGSLKTALHLLHSGLTHFDALRLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Flipping the substrate preference of Hazara virus ovarian tumour domain protease through structure-based mutagenesis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Hazara orthonairovirus
molecule keywords Replicase
total genus 41
structure length 157
sequence length 157
chains with identical sequence C, E, G
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2020-08-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02338 OTU OTU-like cysteine protease
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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