7JMTA

Crystal structure of schistosome bcl-2 bound to abt-737
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
166
structure length
161
Chain Sequence
TADFRLQTSTLCHSFLLASANKQDTDYLTDLLDNTNIDLTCVPNGQEIIHSLLQLVGDFNQRFSEPVAQSLGIDSDKPVDKTALEIFYLEILNGLFEKLNWGRIVAMFAFLRILVLRLSKHGHSDAIQMLIKTTSQYSDEKLKNWINLHDGWSGLIEFSGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Apoptosis
molecule keywords BCL-2 protein
publication title Optimization of Benzothiazole and Thiazole Hydrazones as Inhibitors of Schistosome BCL-2.
pubmed doi rcsb
source organism Schistosoma japonicum
total genus 52
structure length 161
sequence length 166
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2020-08-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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