7JSPA

Crystal structure of the second bromodomain (bd2) of human taf1 bound to atr kinase inhibitor azd6738
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
137
structure length
137
Chain Sequence
SMDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALEEAELESLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the second bromodomain (BD2) of human TAF1 bound to the ATR kinase inhibitor AZD6738
rcsb
molecule tags Gene regulation
source organism Homo sapiens
molecule keywords Transcription initiation factor TFIID subunit 1
total genus 55
structure length 137
sequence length 137
ec nomenclature ec 2.3.1.48: Histone acetyltransferase.
pdb deposition date 2020-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00439 Bromodomain Bromodomain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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