7KMEL

Crystal structure of human alpha-thrombin inhibited with sel2711.
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
25
structure length
25
Chain Sequence
DCGLRPLFEKKSLEDKTERELLESY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of thrombin retro-inhibited with SEL2711 and SEL2770 as they relate to factor Xa binding.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords THROMBIN L-CHAIN
total genus 3
structure length 25
sequence length 25
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 1999-02-26
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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