7KR5A

Cryo-em structure of the crac channel orai in an open conformation; h206a gain-of-function mutation in complex with an antibody
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
150
structure length
127
Chain Sequence
AKLKASSKTSALLSGFAMVAMVEVQLDHDTNVPPGMLIAFAICTTLLVAVAMLALMISTCILHWYIETAWAFSTLLGLILFLLEIAILCWVKFYDLSPPAAWSATVVLIPVMIIFMAFAIHFYRSLV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transport protein/immune system
molecule keywords Calcium release-activated calcium channel protein 1
publication title Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation.
pubmed doi rcsb
source organism Drosophila melanogaster
total genus 51
structure length 127
sequence length 150
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2020-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07856 Orai-1 Mediator of CRAC channel activity
Image from the rcsb pdb (www.rcsb.org)
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