7LF5A

Structure of hyperglycosylated human igg1 fc (fc267)
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
206
structure length
205
Chain Sequence
PSVFLFPPKPKDTLMISRTPEVTCVVVDVNSTDPEVKFNWYVDGVEVHNAKTKPREEQYNTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords IgG1 Fc (Fc267)
total genus 32
structure length 205
sequence length 206
ec nomenclature
pdb deposition date 2021-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07654 C1-set Immunoglobulin C1-set domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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