7LHLA

Cryo-em structure of mycobacterium smegmatis lhr helicase c-terminal domain
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
605
structure length
572
Chain Sequence
PAVVASTSAQLQHLTPERAARDAEGVADLLRLLGPLTEADIAQRCTADNIGAWLDGLHAAKRALPVTYAGQTWWAAVEDIGLLRDGIGVPVPVGVPAAFTESASDPLGDLIGRYARTRGPFTTEQTAARFGLGVRVASDVLSRMAVDGRLILSGEQWCDAQVLKILRRRSLAALRAQVEPVSTDAYARFLPSWQHVGSTNTTGVDGLATVIEQLAGVPIPASAVESLVFPQRVRDYQPAMLDELLASGEVMWSGAGQIGNGDGWVAFHLADTAPLTLTHGAEIEFTDTHRVILETLGHGGAYFFRQLTDGTVEGTAGQELKQALWELIWAGWVTGDTFAPVRAVLSGPRRGTDPTVSGRWSALPAAEPDSTVRAHFQAELLLGRHGVLTKGAVGAEGVPGGFATLYKVLSAFEDAGRCQRGYFVESLGGAQFAVASTVDRLRSYLDNVDPERPEYHAVVLAATDPANPYGAALGWPTDSEAHRPGRKAGALVALVDGRLVWFLERGGRSLLSFGADADAQRAAAGALTDLVSAGRIPSLLVERINGVAVLDPDVDAERAVVQDALLGAGLSR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Oligomeric quaternary structure of Escherichia coli and Mycobacterium smegmatis Lhr helicases is nucleated by a novel C-terminal domain composed of five winged-helix modules.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycolicibacterium smegmatis
molecule keywords ATP-dependent DNA helicase
total genus 105
structure length 572
sequence length 605
chains with identical sequence B, C, D
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2021-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00270 DEAD DEAD/DEAH box helicase
A PF00271 Helicase_C Helicase conserved C-terminal domain
A PF06224 HTH_42 Winged helix DNA-binding domain
A PF08494 DEAD_assoc DEAD/H associated
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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