7M42E

Complex of sars-cov-2 receptor binding domain with the fab fragments of neutralizing antibodies regn10985 and regn10989
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
195
structure length
195
Chain Sequence
TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Viral protein/immune system
molecule keywords REGN10989 antibody Fab fragment light chain
publication title The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies.
pubmed doi rcsb
source organism Homo sapiens
total genus 22
structure length 195
sequence length 195
ec nomenclature
pdb deposition date 2021-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF09408 bCoV_S1_RBD Betacoronavirus spike glycoprotein S1, receptor binding
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the pdb database (?% sequence similarity)

 
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