7MJNB

Cryo-em structure of the sars-cov-2 n501y mutant spike protein ectodomain bound to human ace2 ectodomain (focused refinement of rbd and ace2)
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
201
structure length
201
Chain Sequence
PNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTYGVGYQPYRVVVLSFELLHAPATVCGPKKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.
pubmed doi rcsb
molecule tags Viral protein/hydrolase
source organism Severe acute respiratory syndrome coronavirus 2
molecule keywords Spike glycoprotein
total genus 33
structure length 201
sequence length 201
ec nomenclature
pdb deposition date 2021-04-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09408 bCoV_S1_RBD Betacoronavirus spike glycoprotein S1, receptor binding
B PF16451 bCoV_S1_N Betacoronavirus-like spike glycoprotein S1, N-terminal
B PF19209 CoV_S1_C Coronavirus spike glycoprotein S1, C-terminal
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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