7MN8H

Structure of the her2/her3/nrg1b heterodimer extracellular domain bound to trastuzumab fab
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
51
structure length
49
Chain Sequence
SHLVKCAEKEKTFCVNGGECFMVKSNPSRYLCKCPNEFTGDRCQNYVMA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Signaling protein/immune system
molecule keywords Receptor tyrosine-protein kinase erbB-3
publication title Structures of the HER2-HER3-NRG1 beta complex reveal a dynamic dimer interface.
pubmed doi rcsb
source organism Homo sapiens
total genus 12
structure length 49
sequence length 51
ec nomenclature
pdb deposition date 2021-04-30
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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