7OJJL

Lassa virus l protein with endonuclease and c-terminal domains in close proximity [mid-link]
Total Genus 442
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
442
sequence length
2208
structure length
1785
Chain Sequence
MEDDMACVKDLVSKYLADNERLSRQKLAFLVQTEPRMLLMEGLKLLSLCIEIDSCNANGCEHNSEDKSVERILHDHGILTPSLCFVVPDGYKLTGNVLILLECFVRSSPANFEQKYIEDFKKLEQLKEDLKSVDINLIPLIDGRTSFYNEQIPDWVNDKLRDTLFSLLRYAQESNSLFEESEYSRLCESLSMTSGRLSGVESLNVLLDNRSSHYEEIIASCHQGINNKLTAHEVKLQIEEEYQVFRNRLRKGEITGQFLKVDKSRLLNDFNNLYVDEVTATKDNIEHLIYQFKRASPILRFLYANIGEGNGEERHHTIKECQMQYWRSFLNKVKSLRKLLLIFDALILLASIHDQTRHKCSKGWLGSCFISVNDRLVSLESTKRDLEKWVGRRQQSERSPPDKNQILISMFQKTILKATAALKDVGISVEHYKINMEVICPDSYDLILNFDVSGVVPTISYQRTEDEKFPFIMGGVELLESTDLERLSSLSLALVNSMKTSSTVCKEAYCQEFLLSGAEFQLIYQKTGECSKCYAINDNRVGEICSFYADPKRYFPAIFSAEVLQTTVSTMISWVKDCSELEEQLCNINSLTKMILVLILAHPSKRSQKLLQNLRYFIMAYVSDYHHKDLIDKLREELITDVEFLLYRLVRALVNLILSEDVKSMMTNRFKFILNISYMCHFITKETPDRLTDQIKCFEKFLEPKLEFGHVSINPADVATEEELDDMVYNAKKFLSKEGCTSIKGPDYKKPGVSKRFLSLLTSSFNNGSLFKESEVKREIKDPLVTATALDLASNKSVVVNKYTDGSRVLNYDFNKLTALAVSQLTEVFSRKGKHLLNKQDYDYKVQQAMSNLVLGADLDEILLDGGASVYFDQLKETVERIIDQYDMGRLSDDVRISERESNSEALSKALSLTNCTTAMLKNLCFYSQESPQSYSSTGPDTGRLKFSLSYKEQVGGNRELYIGDLRTKMFTRLIEDYFEALSLQLSGSCLNNEREFENAILSMKLNVSLAHVSYSMDHSKWGPMMCPFLFLATLQNLIFLSKDLQADIKGRDYLSTLLTWHMHKMVEIPFNVVSAMMKSFIKAQLGLKKKTTQSITEDFFYSNFQIGVVPSHVSSILDMGQGILHNTSDFYALISERFINYAISCICGGTIDAYTSSDDQISLFDQVLTELMQRDPEEFKTLIEFHYYMSDQLNKFVSPKSVIGRFVAEFKSRFYVWGDEVPLLTKFVAAALHNIKCKEPHQLAETIDTIIDQSVANGVPVHLCNLIQKRTLSLLQYARYPIDPFLLNCETDVRDWVDGNRSYRIMRQIERLIPDACGRIRSMLRKLYNKLKTGQLHEEFTTNYLSSEHLSSLSNLCELLGVEPPSESDLEFSWLNLAAHHPLRMVSSIASGFVGLCRTLGSKCVRGPNKESLYIKSIQSLISDIQGIEPLIDSHGVQYWRVPLNIRDGNEGVISYFRPLLWDYMCISLSTAIELGAWVLGEPKKVRVLEFFKHNPCDYFPLKPAAGLNHIIHSLRRLYPSVFEKHILPFMSDLASTKMKWSPRIKFLDLCVALDVNCEEHYIVLSSELRLSHTRTHSTSDAVDNFMRQIYFESYVRSFVATTRTLGSFTWFPHKTSVPEGEGLQRLGPFSSFVEKAIHKGIERPMFKHDLMPVPLVVHRGGLWECDKKLASFTPVVQDQDLEMFVKEVGDSSLDLLIGALSAMILDRLKLRMQWSEVDIVSMLKAAMPSNSVKVLNAVLEAVDDWVDFKGYALCYSKSRKKVMVHSSGGKLRLKGRTCEELVK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
pubmed doi rcsb
molecule tags Viral protein
source organism Lassa mammarenavirus
molecule keywords RNA-directed RNA polymerase L
total genus 442
structure length 1785
sequence length 2208
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2021-05-16
Image from the rcsb pdb (www.rcsb.org)
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