7OLJAAA

Tankyrase 2 in complex with an inhibitor (oul219)
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
161
structure length
161
Chain Sequence
GSGTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Poly [ADP-ribose] polymerase tankyrase-2
total genus 47
structure length 161
sequence length 161
chains with identical sequence BBB
ec nomenclature ec 2.4.2.-:
pdb deposition date 2021-05-20
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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