7OUFA

Structure of the stlv intasome:b56 complex bound to the strand-transfer inhibitor xz450
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
278
structure length
258
Chain Sequence
SPAKLHSFTHCGQAALTLHGATTTEALNILHSCHACRIRRGLLPNHIWQGDITHFKYKNTLYRLHVWVDTFSGSVSATHKKRETSSEAISSLLHAIAHLGRPSHINTDNGPAYASQEFQHACTSLAIRHTTHIPVERTNGILKTLLYKYFSDNPNLPMDNALSVALWTINHLNVLTHCQKTRWQLHHSPRLPPIPEEKPVTTSKTHWYYFKIPGLNSRQWKGPQRALQEAAGAALIPVSDTAAQWIPWKLLKRAVCPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Viral protein
molecule keywords Integrase
publication title Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures.
pubmed doi rcsb
source organism Simian t-lymphotropic virus 1
total genus 59
structure length 258
sequence length 278
chains with identical sequence B, D, E
ec nomenclature
pdb deposition date 2021-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00552 IN_DBD_C Integrase DNA binding domain
A PF00665 rve Integrase core domain
A PF02022 Integrase_Zn Integrase Zinc binding domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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