7QDPE

Crystal structure of flt3 t343i in complex with the canonical ligand fl
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
368
structure length
332
Chain Sequence
LLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGEESPAVVKKEEKVLHELFGMDIRCCARNELLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSVARNDTGYYTCSSSKHPSQSALVIIVEKGFINATEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQGYSISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWSPNCTEEITEGVWNRVSSSTMSEAIKGFLVKCCAYNSLGTSCETILLNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of FLT3 T343I in complex with the canonical ligand FL
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Fms-related tyrosine kinase 3 ligand
total genus 39
structure length 332
sequence length 368
chains with identical sequence F, G, H
ec nomenclature ec 2.7.10.1: receptor protein-tyrosine kinase.
pdb deposition date 2021-11-27
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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