7S3ZA

Structure of rat neuronal nitric oxide synthase heme domain in complex with n2-((3-((2-aminoquinolin-7-yl)methoxy)phenoxy)methyl)pyridine-2,6-diamine
Total Genus 131
50100150200250300350400020406080100120
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
418
structure length
411
Chain Sequence
RFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPSDVRTKDQLFPLAKEFLDQYYSSIKRFGSKAHMDRLEEVNKEIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVW
50100150200250300350400400300200100
020406080100120Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYS1 (301-304)TI1 (305-308)TI2 (306-309)S2 (311-314)3H1 (316-319)AH1 (351-369)AH2 (375-391)TVIII1 (335-338)TII1 (371-374)TI3 (327-330)TI4 (332-335)AH3 (398-411)Updating...
connected with : NaN
molecule tags Oxidoreductase/inhibitor
source organism Rattus norvegicus
publication title Selective anti-MRSA inhibitors targeting bacterial nitric oxide synthase
rcsb
molecule keywords Nitric oxide synthase, brain
total genus 131
structure length 411
sequence length 418
chains with identical sequence B
ec nomenclature ec 1.14.13.39: nitric-oxide synthase (NADPH).
pdb deposition date 2021-09-08
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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