7S63A

Native-form oocyte/egg alpha-2-macroglobulin (a2moo) tetramer
Total Genus 210
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
210
sequence length
1420
structure length
1420
Chain Sequence
KVQYALTIPALLKSGETQRACVNLIGYHQPLALSVVLEHQRVNISIFSEKVQPPHYFKCNKFMVPTVITNAPDFVTLSVSGGGEDIKDRKAVVIAPLNTICLIQMDKPVYKPGCKVRFRLISLNTMLLPISEKYTAVYLEDPSGSRIAQWQNQESVGGVVQLEFPLISDAAPGSYTITAEGESCESARQGFTVDEYILPRFSVIVDPPNTISILDDILTLNVSAIYTYGQPVPGSVTIKCCREASSYYGRKGNCFKGNRGICTNITGELGPDGAFYGVVSLLPFQMGQSGFQMSLGVALTVTEEGTGIQVTHQFFIMITSQLATLIFDYDALKEFYKRGIPYLVKVILTDANDNPMANEQVEVELAGKTIGAVLTDKEGRAEYAIDTSSFVQENFTVVVSYENPHQCYYTEWEGPDFPTAQHFVMRFYSETGSFLDIQGSSVELNCGQVHNISVRYILSLDGMGEGATTATFYYLAMSRAKIVQHGQRDVHLNQSKSGLFNIGLNVTSDLAPGAELIVYCILDLELIADTISLDIEKCFQNQVSLSFSDDLGPTASNVSLNLSAAPGSLCGVKVIDSSLLLINPYESLSASGVYYSIPYLSLFGYNYGGFNLEEPEPPCEDPNTVIFCKGRYYLPVSSSTEGDTYQNLRRVGLVLGTSSKIRKPVVCGMEAKFSVPRKSSGESDFGSSLSNGHVETLRKNFSETFLWRLVSVDSEGQNTITETVPDTITKWQGSMFCVSEKEGFGITKYSANFTSFLPFFVELSLPYSLTREEILVMKAFVSNYLEECIKIIVTLQPSADFEVIPQDVKQDQCICSGGRSSYSWNIIASSLGRISFIVSAETTHIGASCDGPSDQSQSTRKDTVIQTILVQPEGIRKEETSSNLVCVEDSNVEMPINLTLPENIVQGSASAFVTFVGDVLGLPLSNLQNLLQMPYGCGEQNLARMAPIPYVLEYLNNTNQLTDELLQTAVQFLNEGYYRQLRYKLPSGAYDAFWSSPSDGSSWLSAYTFKTFEKAKKYIYVDGKIQQQTLLYLQTSQKLDNGCFKAEGNLFMRQCGQERDLCFTAYLAIALLESNYSSGMTLLDDALGCLEAAMSSASTLYFKSYTVYVFTLVQNWEIRNTLLNELKSKVVSERGTLHWEREDKLGQEGIPLYYPNYSPAEVEITAYMLLSIAKGSDPTHDDLTYMAQISVWLIQQQNSYGGFRSTQDTVVALQALAFYAQLLFKSNAHHNVFLRSEYGDVGQLNLSEHNRLVVQRLQLPEVSGNYSISINGTGCCLVQSTIRYNIPVPKENSAFYVAADSVSKNCLNGVAYTITITVSVSYRGLRNETNMVIIDIQMLSGYQADYPSLRQLENSQQVSKTEEQDNHVFLYLNAVPLKTIQLSFKVLIGSRVLNVKSASVYVYDYYETGENGFASYSQPC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Mechanics of the Alpha-2-Macroglobulin Transformation.
pubmed doi rcsb
molecule tags Protein binding
molecule keywords Alpha 2-Macroglobulin
total genus 210
structure length 1420
sequence length 1420
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2021-09-13
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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