7SJ3A

Structure of cdk4-cyclin d3 bound to abemaciclib
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
294
structure length
273
Chain Sequence
ATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSDREIKVTLVFEHVDQDLRTYLDKAPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFPPRGPRPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of CDK4-Cyclin D3 bound to abemaciclib
rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Cyclin-dependent kinase 4
total genus 70
structure length 273
sequence length 294
ec nomenclature ec 2.7.11.22: cyclin-dependent kinase.
pdb deposition date 2021-10-15
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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