7SR9B

Human alpha-thrombin with 180- and 220- loops replaced with homologous loops from protein c
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
253
structure length
253
Chain Sequence
IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGILGDRQDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCGLLHNYGFYTHVFRLKKWIQKVIDQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The active site region plays a critical role in Na + binding to thrombin.
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords Thrombin light chain
total genus 55
structure length 253
sequence length 253
ec nomenclature ec 3.4.21.5: thrombin.
pdb deposition date 2021-11-08
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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