7T68A

Co-crystal structure of chaetomium glucosidase with compound uv-5
Total Genus 263
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
263
sequence length
778
structure length
765
Chain Sequence
LHSEIGRLNNQSLLWGPYRPNIYFGTRPRIGKSLMTGLMWGKIESYTDFQHTVRYTCEQNEGMKGYGWDEYDPRRGGIQSIHDIQNGLDITTSFVKIPGGAHGGSWAARIKGTLNDDAPKDQKTIVVFYVSQEGENSELEAVPSENEFGYEGDVILKGRSEALGNYKLVVTKGKGVIPQSDHDLSRLRGPGQTVVQSLTYPDEVLWQAKPILFQQLKAGIDWLVENKYDVADPPPPWQVYLLANKPGSGNVHIVQKVFEGDFEFDILFSSESAGKEVTSKDLEREVKQATEVFGERFARVFDLKAPFQGDNYKKFGKSMFSNLIGGIGYFYGHSLVDRSYAPEYDEENEGFWEDAAEARARHQEALEGPYELFTSIPSRPFFPRGFLWDEGFHLLPIADWDIDLALEIIKSWYNLMDEDGWIAREQILGAEARSKVPKEFQTQYPHYANPPTLFLVLDNFVERLRKLDETLSTASVDNPEVGLEYLRRLYPLLRRQFDWFRKTQAGDIKSYDREAYSTKEAYRWRGRTVSHCLTSGLDDYPRPQPPHPGELHVDLMSWVGVMVKSLISIGSLLGATEDVEFYTKVLDAIEHNLDDLHWSEKEGCYCDATIDEFEEHKLVCHKGYISLFPFLTGLLKPDSPKLGKLLALIGDESELWSPYGLRSLSKKDEFYGTAENYWRSPVWININYLAIVQLYNIATQDGPYKETARDLYTRLRKNIVETVYRNWEETGFAWEQYNPETGKGQRTQHFTGWTSLVVKIMSGHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase/inhibitor
molecule keywords Chaetomium alpha glucosidase
publication title Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.
pubmed doi rcsb
source organism Chaetomium thermophilum var. thermophilum dsm 1495
total genus 263
structure length 765
sequence length 778
chains with identical sequence B
ec nomenclature ec 3.2.1.106: mannosyl-oligosaccharide glucosidase.
pdb deposition date 2021-12-13
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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