7T9UA

Crystal structure of hsting with an agonist (shr169224)
Total Genus 61
204060801001201401600102030405060
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
191
structure length
177
Chain Sequence
FNVAHGLAWSYYIGYLRLILPELQARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQVYSNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPAFSLSQEVLRHLRQEEKEEVTV

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
AH1 (155-166)EMPTYAH2 (168-190)Updating...
connected with : NaN
molecule tags Immune system/inhibitor
source organism Homo sapiens
publication title SHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis.
pubmed doi rcsb
molecule keywords Stimulator of interferon genes protein
total genus 61
structure length 177
sequence length 191
ec nomenclature
pdb deposition date 2021-12-20
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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