7TQQA

Structure of human trex1-dna complex
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
227
structure length
212
Chain Sequence
PGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of human TREX1 DNA degradation and autoimmune disease.
pubmed doi rcsb
molecule keywords Three-prime repair exonuclease 1
molecule tags Hydrolase/dna
source organism Homo sapiens
total genus 67
structure length 212
sequence length 227
chains with identical sequence B, E, F
ec nomenclature ec 3.1.11.2: exodeoxyribonuclease III.
pdb deposition date 2022-01-26
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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