7TRBC

Crystal structure of farnesoid x-activated receptor complexed with compound-32 aka (1s,3s)-n-({4-[5-(2-fluoropr opan-2-yl)-1,2,4-oxadiazol-3-yl]bicyclo[2.2.2]octan-1-yl}m ethyl)-3-hydroxy-n-[4'-(2-hydroxypropan-2-yl)-[1,1'-biphen yl]-3-yl]-3-(trifluoromethyl)cyclobutane-1-carboxamide
Total Genus 3
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
11
structure length
11
Chain Sequence
HQLLRYLLDKD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Discovery of BMS-986339, a Pharmacologically Differentiated Farnesoid X Receptor Agonist for the Treatment of Nonalcoholic Steatohepatitis.
pubmed doi rcsb
molecule tags Nuclear protein
source organism Homo sapiens
molecule keywords Bile acid receptor
total genus 3
structure length 11
sequence length 11
chains with identical sequence D
ec nomenclature ec 2.3.1.48: histone acetyltransferase.
pdb deposition date 2022-01-28
Image from the rcsb pdb (www.rcsb.org)
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...