7TW8A

Structure of nsp14 n7-methyltransferase domain fused with telsam bound to sah
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
303
structure length
264
Chain Sequence
LPAHLRLQPIYWSRDDVAQWLKWAENEFSLRPIDSNTFEMNGKALLLLTKEDFRYRSPHSGDELYELLQHILAQPAAGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDKSAFVNLKQLPFFYYSDSPCESHYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development.
pubmed doi rcsb
molecule tags Viral protein
source organism Severe acute respiratory syndrome coronavirus 2
molecule keywords Transcription factor ETV6,Proofreading exoribonuclease nsp14 chimera
total genus 81
structure length 264
sequence length 303
ec nomenclature ec 2.1.1.57: methyltransferase cap1.
pdb deposition date 2022-02-06
Image from the rcsb pdb (www.rcsb.org)
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