7U5BI

Structure of human klk5 bound to anti-klk5 fab
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
217
structure length
149
Chain Sequence
TQPWQAALLLRGAVLVHPQWLLTAAHFRVRLGQQMFQGVKSIHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSCLNISVLSQKRCEDAYPRQIDDTMFCAGDGPVVCNGSLQGLVSPNRPGVYTNLCKFTKWIQETIQANS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/immune system
molecule keywords anti-KLK5 Fab Heavy Chain
publication title Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis.
pubmed doi rcsb
source organism Synthetic construct
total genus 30
structure length 149
sequence length 217
chains with identical sequence J
ec nomenclature ec 3.4.21.-:
pdb deposition date 2022-03-02
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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