7UKZA

Cdk11 in complex with small molecule inhibitor ots964
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
303
structure length
295
Chain Sequence
EEFQCLNRIEEGTYGVVYRAKDKEIVALKRLKMEKEKEFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/inhibitor
molecule keywords Cyclin-dependent kinase 11B
publication title Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964.
pubmed doi rcsb
source organism Homo sapiens
total genus 78
structure length 295
sequence length 303
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.7.11.22: cyclin-dependent kinase.
pdb deposition date 2022-04-03
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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