7VH1A

Cryo-em structure of machupo virus dimeric l-z complex
Total Genus 312
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
312
sequence length
1815
structure length
1612
Chain Sequence
DEYVQELKGLIRKHIPDRCEFAHQKVTFLSQVHPSPLLTEGFKLLSSLVELESCEAHACQANTDQRFVDVILSDNGILCPTLPKVIPDGFKLTGKTLILLETFVRVNPDEFEKKWKADMSKLLNLKHDLQKSGVTLVPIVDGRSNYNNRFVADWVIERMRWLLIEILKASKSMLEDQEYQRLIHSLSNVKNQSLGLENLEHLKRNSLDYDERLNESLFIGLKGDIRESTVREELIKLKMWFKDEVFSKGLGKFKLTDRRELLESLSSLGAHLDSDVSSCPFCNNKLMEIVYNVTFSSVERTNIEKHYLSVLSLCNKIKGLKVFNTRRNTLLFLDLIMVNLMVDISESCQDAIESLRKSGLIVGQMVMLVNDRVLDILEAIKLIRKKIGTNPNWVKNCSKILERSHPEIWLQLNTLIRQPDFNSLISIAQYLVSDRPIMRYSKICRHKLFQEMSSFEQMRLFKTLSSISLSLINSMKTSFSSRLLVNEFGNVRLRECYAQRFYLAESLVGFLFYQKTGERSRCYSVYLSDNGVMSEQGSFYCDPKRFFLPVFSDEVLAGMCEEMTSWLDFDTGLMNDTGPILRLLVLAILCSPSKRNQTFLQGLRYFLMAFANQIHHIDLISKLVVECKSSSEVVVQRLAVGLFIRLLGGESDASSFFSRRFKYLLNVSYLCHLITKETPDRLTDQIKCFEKFIEPKVKFGCAVVNPSLNGKLTVDQEDIMINGLKKFFSKSLRDTEDVQTPGVCKELLNYCVSLFNRGKLKVSGELKNNPFRVVIPKLDELGNILSTYDKEKLVSACVSSMAERFKTKGRYNLDPESTDYLILKNLTSQEELSLMYETLTEEQVESFNEIKYDVQVALAKMADNSPFGVMKEIRAEVSLHEVKDFDPDVLPSDVYKELCDAVYKSSEKCNFFLEEVLDVCPLGLLLKNLTTSSYMEEEYFMCFKYLLIQGHFDQADKLDKSYFTNAALRNLCFYSEDSPTEFTSISSNSGNLKFGLSYKEQVGSNRELYVGDLNTKLMTRLVEDFSEAVGNSMKYTCLNSEKEFERAICDMKMAVNNGDLSCSYDHSKWGPTMSPALFLALLQMLELRTPVDRSKIDLDSVKSILKWHLHKVVEVPINVAEAYCIGSLSEEFFHQTMQLSGQIPSHIMSVLDMGQGILHNTSDLYGLITEQFLCYALDLLYDVIPVSYTSSDDQITLVKTPSAAEWLEMICFHEFLSSKLNKFVSPKSVIGTFVAEFKSRFFVMGEETPLLTKFVSAALHNVKCKTPTQLSETIDTICDQCIANGVSTKIVARISKRVNQLIRYSGYGDTPFGAIEDQDVKDWVDGSRGYRLQRKIEAIFYDDKETSFIRNCARKVFNDIKRGRIFEENLINLIGRGGDEALTGFLQYAGCSEQEVNRVLNYRWVNLSSFGDLRLVVPTLIKTLQSKLSRSSVASGFIGFCKSMGSKCVRDGKGGFLYIKEVYSGINVCICEICALKPKIIYCNDSLNKVSQFSKPILWDYFSLVLTNACELGEWVFSTVKEPQLNNQNFFWAVKPKVVRQIEDQLGMNHVLQSIRRNYPVLFDELKFLDVCIALDMMNENLGIISHLLKTRDNSVYIVKQSDCALAHIRQS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Machupo virus polymerase in complex with matrix protein Z
rcsb
molecule tags Viral protein
source organism Machupo virus
molecule keywords RNA-directed RNA polymerase L
total genus 312
structure length 1612
sequence length 1815
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2021-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06317 Arena_RNA_pol Arenavirus RNA polymerase
A PF17296 ArenaCapSnatch Arenavirus cap snatching domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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