7WD4A

Crystal structure of the ilheus virus helicase: implications for enzyme function and drug design
Total Genus 146
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
446
structure length
437
Chain Sequence
GPGSEAFTPDMLKKRRLTILDLHPGAGKTRRVIPQIVRECVKARLRTVILAPTRVVAAEMAEALRGLPIRYQGNEIVDVMCHATLTQRLLTPAKVPNYNVFVMDEAHFTDPASIAARGYISTKVELGEAAAIFMTATPPGTTDPFPDSNAPIIDQEAEIPDRAWNSGFEWITEYTGKTVWFVPSVRMGNEIAMCLTKAGKKVIQLNRKSYDSEYQKCKGNDWDFVITTDISEMGANFGAHRVIDSRKCVKPVILDGDDRVLMNGPAPITPASAAQRRGRIGRDPTQSGDEYFYGGPTTTDDTGHAHWIEAKILLDNIQLQNGLVAQLYGPERDKVFTTDGEYRLRSEQKKNFVEFLRTGDLPVWLSYKVAEAGYAYTDRRWCFDGPANNTILEDNNEVEIWTRQGEKRILRPRWSDARVYCDNQALRSFKEFAAGKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of the Ilheus virus helicase: implications for enzyme function and drug design
rcsb
molecule tags Hydrolase
source organism Ilheus virus
molecule keywords NS3 helicase
total genus 146
structure length 437
sequence length 446
ec nomenclature ec 3.4.21.91: flavivirin.
pdb deposition date 2021-12-21
Image from the rcsb pdb (www.rcsb.org)
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...