8A58A

X-ray structure of trim21 ring e3 ligase in complex with e2 enzyme ube2w
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
144
structure length
140
Chain Sequence
ASMQKRLQKELLALQNDPPPGMTLNENSITQWIVDMEGAPGTLYEGEKFQLLFKFSSRYPFKSPQVMFTGENIPVHPHVYSNGHIKLSILTEDWSPALSVQSVCLSIISMLSSCKEKRRPPDNSFYVRTCNKNPKKTKWW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords Ubiquitin-conjugating enzyme E2 W
total genus 35
structure length 140
sequence length 144
chains with identical sequence B
ec nomenclature ec 2.3.2.23: E2 ubiquitin-conjugating enzyme.
pdb deposition date 2022-06-14
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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