8AU5A

C-met f1200i mutant in complex with tepotinib
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
280
structure length
265
Chain Sequence
QHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLKIHCAVKSLNREVSQFLTEGIIMKDFSHPNVLSLLGICLRSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKIVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Biophysical and structural characterization of the impacts of MET phosphorylation on tepotinib binding.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Hepatocyte growth factor receptor
total genus 73
structure length 265
sequence length 280
ec nomenclature ec 2.7.10.1: receptor protein-tyrosine kinase.
pdb deposition date 2022-08-25
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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