8DPTA

The structure of the il-11 signalling complex, with full-length extracellular gp130
Total Genus 51

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
398
structure length
398
Chain Sequence
LLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYS3 (20-27)S1 (8-10)TIV1 (9-12)S2 (15-17)TII1 (17-20)TI1 (61-64)S6 (57-61)S4 (43-47)S5 (50-51)3H2 (54-56)TIV7 (86-89)TIV3 (46-49)TIV5 (74-77)S7 (64-72)S10 (99-101)S9 (91-97)S8 (78-83)TIV6 (84-87)S12 (121-125)TIV8 (107-110)S11 (108-115)3H3 (194-196)TI3 (156-159)S16 (159-161)TVIII1 (154-157)S13 (135-142)S15 (150-151)S14 (145-146)TI2 (142-145)TIV9 (153-156)S19 (190-192)TII3 (167-170)S18 (183-186)S20 (198-199)S21 (204-209)TIV11 (214-217)S25 (261-264)S22 (218-223)S23 (233-241)3H4 (226-229)3H5 (252-254)TI5 (241-244)TIV12 (268-271)S26 (272-281)S27 (295-298)S28 (310-316)TII4 (319-322)S30 (343-350)S34 (385-386)TII5 (350-353)S33 (374-382)AH1 (30-36)TII2 (115-118)S17 (172-180)TI4 (180-183)S24 (248-249)TI6 (281-284)S32 (364-369)S29 (323-329)TI7 (382-385)3H1 (40-42)S31 (355-360)AH2 (334-337)Updating...
connected with : NaN
molecule tags Cytokine
source organism Homo sapiens
publication title Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant
doi rcsb
molecule keywords Interleukin-6 receptor subunit beta
total genus 51
structure length 398
sequence length 398
chains with identical sequence D
ec nomenclature
pdb deposition date 2022-07-17
Image from the rcsb pdb (www.rcsb.org)
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