8EGZA

Engineered tyrosine synthase (tmtyrs1) derived from t. maritima trpb with ser bound as the amino-acrylate intermediate
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
385
structure length
385
Chain Sequence
GNFGPYGGQNVPEILMGALEELEAAYEGIMKDESFWKEYNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRITAGTGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWITNLQTTYYVPGSVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACVSGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQASHSVSAGLDYPGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Noncanonical L-tyrosine synthesis by evolved tryptophan synthases
rcsb
molecule tags Biosynthetic protein
source organism Thermotoga maritima
molecule keywords Tryptophan synthase beta chain 1
total genus 161
structure length 385
sequence length 385
chains with identical sequence B
ec nomenclature ec 4.2.1.20: tryptophan synthase.
pdb deposition date 2022-09-13
Image from the rcsb pdb (www.rcsb.org)
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