8EO6A

Crystal structure of metagenomic class a beta-lactamase precursor lra-5 in complex with ceftazidime at 2.35 angstrom resolution
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
268
structure length
268
Chain Sequence
EAISMLTERLSSIINAAGGDIGIAVIHVETGHTTAIQGTTQLPLYSVFKLPLAIAVLKEIEENRLQLDRKVRVTPADVAPGWTANAAMWRRPIDRTVAQLIEVSIIRSDNTSSDKLLQLVGGPAAVTHRMRALGFPNIEIVSTVREFSENRTRPNTGSAEDLARLLVQLQKGELLQPQHSALLLGFMHRATTGTERLRGSLPVGTPVADKTGTGDAGVVTNDVGIITLPKGQGHLAIAVLISGSKLSPAAQEKLIAEIARAAYDAHVS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Antimicrobial protein
molecule keywords LRA-5
publication title Playing beta-Lactamase Evolution: Metagenomic Class A beta-Lactamase LRA-5 is an Inactive Enzyme Capable of Rendering an Active beta-Lactamase by Introduction of Y69Q and V166E Substitutions
rcsb
source organism Uncultured soil bacterium
total genus 93
structure length 268
sequence length 268
chains with identical sequence B
ec nomenclature
pdb deposition date 2022-10-02
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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