8FURA

Crystal structure of human ido1 with compound 11
Total Genus 134
50100150200250300350020406080100120140
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
134
sequence length
388
structure length
362
Chain Sequence
EYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQDLMNFLKTVRSTTEKSLLK
5010015020025030035035030025020015010050
020406080100120Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYTII'1 (21-24)AH2 (54-61)AH1 (37-52)O2 (142-144)TII'2 (92-95)TI2 (67-70)TVIII1 (68-71)AH3 (73-92)AH7 (193-220)TIV3 (95-98)S1 (102-103)AH10 (287-298)AH4 (105-118)TIV6 (250-253)O1 (121-123)S2 (135-136)AH5 (126-130)TI3 (130-133)TVIII2 (136-139)3H2 (145-147)TI4 (138-141)AH11 (301-312)AH6 (160-190)S4 (248-249)AH8 (223-229)3H3 (231-234)TIV5 (241-244)TI5 (240-243)TII2 (249-252)AH12 (316-323)TIV1 (18-21)TIV2 (25-28)3H1 (34-36)TIV4 (237-240)S3 (148-149)AH13 (326-359)TI6 (243-246)TII1 (155-158)AH9 (268-277)3H4 (264-266)Updating...
connected with : NaN
molecule tags Oxidoreductase/inhibitor
source organism Homo sapiens
publication title Synthesis and biological evaluation of biaryl alkyl ethers as inhibitors of IDO1.
pubmed doi rcsb
molecule keywords Indoleamine 2,3-dioxygenase 1
total genus 134
structure length 362
sequence length 388
chains with identical sequence B, C, D
ec nomenclature ec 1.13.11.52: indoleamine 2,3-dioxygenase.
pdb deposition date 2023-01-18
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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