8G42B

Kras g12c complex with gdp imaged on a cryo-em imaging scaffold
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
165
structure length
165
Chain Sequence
MTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of the KRAS Protein Cancer Target at 3 Angstrom Resolution by Cryo-EM Scaffolding
rcsb
molecule tags Signaling protein
source organism Synthetic construct
molecule keywords RCG-33 - Cryo-EM imaging scaffold subunit B fused to DARPin
total genus 50
structure length 165
sequence length 165
ec nomenclature ec 3.6.5.2: small monomeric GTPase.
pdb deposition date 2023-02-08
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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