8G6IC

Coagulation factor viii bound to a patient-derived anti-c1 domain antibody inhibitor
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
215
structure length
215
Chain Sequence
EVQLVESGGGVVQPGRSLRLSCVDSGLTFSSYGMHWVRQAPGAGLEWVAVISYDGNDKYYADSVKGRFAISRDNAKNTLYLQMNSLTIEDTAVYYCAKDLIESNIAEAFWGQGTLVTVSSKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTATYTCNVDHKPSNTKVDKRV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
molecule keywords Coagulation factor VIII chimera from human and pig
publication title Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor.
pubmed doi rcsb
source organism Sus scrofa
total genus 10
structure length 215
sequence length 215
ec nomenclature
pdb deposition date 2023-02-15
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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