8HMAH

Cryo-em structure of human high-voltage activated l-type calcium channel cav1.2 in complex with tetrandrine (tet)
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
186
structure length
165
Chain Sequence
DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRLAEVQSEIERIFELARTLLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
pubmed doi rcsb
molecule tags Membrane protein
source organism Homo sapiens
molecule keywords Voltage-dependent L-type calcium channel subunit alpha
total genus 41
structure length 165
sequence length 186
ec nomenclature
pdb deposition date 2022-12-02
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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