8I0MA

Structure of cdk6 in complex with inhibitor
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
291
structure length
260
Chain Sequence
QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVPLSTIREVAVLRHLETFEHPNVVRLFDVCTLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLAVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of CDK6 in complex with inhibitor
rcsb
molecule tags Cell cycle/inhibitor
source organism Homo sapiens
molecule keywords Cyclin-dependent kinase 6
total genus 69
structure length 260
sequence length 291
ec nomenclature ec 2.7.11.22: cyclin-dependent kinase.
pdb deposition date 2023-01-11
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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