8I5FC

Crystal structure of the dhr-2 domain of dock10 in complex with cdc42 (t17n mutant)
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
178
structure length
178
Chain Sequence
MQTIKCVVVGDGAVGKNCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the dual GTPase specificity of the DOCK10 guanine nucleotide exchange factor.
pubmed doi rcsb
molecule tags Signaling protein
source organism Mus musculus
molecule keywords Dedicator of cytokinesis protein 10
total genus 55
structure length 178
sequence length 178
chains with identical sequence D
ec nomenclature ec 3.6.5.2: small monomeric GTPase.
pdb deposition date 2023-01-25
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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