8ITPB

Crystal structure of usp47 catalytic domain complex with ubiquitin
Total Genus 79
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
415
structure length
343
Chain Sequence
IPVDENGHRYVGLVNQAMTSYLNSLVQSLYMTPEFRNAMYDWERKKAEQSIPCQLQKLFLLLQTSENDSLETKDLTQSFGWTSNEHDVQELCRLMFDALEHKWKGTEHEKLIQDLYRGTMEDFVACLKCGRESVKTDYFLDLPLAVKPFGAIHAYKSVEEALTAFVQPELLDGSNQYMCENCKSKQDAHKGLRITQFPYLLTIQLKRFDFDYNTMHRIKLNDKMTFPDVLDLNDYVNVCVGQPIDHAAVDDIVKTSGDNVYELFSVMVHSGNAAGGHYFAYIKNLDQDRWYVFNDTRVDFATPLEIEKSFGGHSNTNAYMLMYRRIDPKRNARFILSNQLPQH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and functional characterization of USP47 reveals a hot spot for inhibitor design
doi rcsb
molecule tags Hydrolase/inhibitor
source organism Homo sapiens
molecule keywords Ubiquitin
total genus 79
structure length 343
sequence length 415
chains with identical sequence D
ec nomenclature ec 3.4.19.12: ubiquitinyl hydrolase 1.
pdb deposition date 2023-03-22
Image from the rcsb pdb (www.rcsb.org)
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...