8OTMA

Structure of inha from mycobacterium tuberculosis in complex with n-((1-(3-hydroxy-4-phenoxybenzyl)-1h-1,2,3-triazol-4-yl)methyl)-2-oxo-2h-chromene-3-carboxamide
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
268
structure length
268
Chain Sequence
TGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mycobacterium tuberculosis
molecule keywords Enoyl-[acyl-carrier-protein] reductase [NADH]
total genus 103
structure length 268
sequence length 268
chains with identical sequence B, C, D
ec nomenclature ec 1.3.1.9: enoyl-[acyl-carrier-protein] reductase (NADH).
pdb deposition date 2023-04-21
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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