8P4ZA

Crystal structure of the human cdk7 kinase domain in complex with ldc4297
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
300
structure length
272
Chain Sequence
RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKINRTALREIKLLQELSHPNIIGLLDAFSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the human CDK7 kinase domain in complex with LDC4297
rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Cyclin-dependent kinase 7
total genus 68
structure length 272
sequence length 300
chains with identical sequence B
ec nomenclature ec 2.7.11.22: cyclin-dependent kinase.
pdb deposition date 2023-05-23
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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