8PI6A

Crystal structure of the monomeric zinc free human insulin a22k, b3e, b26e, b29r, desb30 precursor with a ser-glu-asp-trp-trp-arg c-peptide and a glu-glu-gly-glu-pro-arg n-terminal extension
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
60
structure length
60
Chain Sequence
GEPRFVEQHLCGSHLVEALYLVCGERGFFETPRSEDWWRGIVEQCCTSICSLYQLENYCN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular engineering of insulin for recombinant expression in yeast.
pubmed doi rcsb
molecule keywords Insulin B chain,Insulin A chain
molecule tags Hormone
source organism Homo sapiens
total genus 17
structure length 60
sequence length 60
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2023-06-21
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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