8SVRA

Crystal structure of pregnane x receptor ligand binding domain in complex with sjpyt-326
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
318
structure length
282
Chain Sequence
GLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITSLTERHKILHRLLQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR
rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Pregnane X receptor ligand binding domain fused to SRC-1 coactivator peptide
total genus 99
structure length 282
sequence length 318
chains with identical sequence B
ec nomenclature
pdb deposition date 2023-05-17
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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