8TPNA

Nhtmem16 lipid scramblase in lipid nanodiscs with msp2n2 scaffold protein in the presence of ca2+ (intermediate state)
Total Genus 178
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
178
sequence length
697
structure length
551
Chain Sequence
SNFGVDFVIHYKVPAAERDEAEAGFVQLIRALTTVGLATEVRHGENESLLVFVKVASPDLFAKQVYRARLGDWLHGVRVAQALQDEPVVEAERLRLIYLMITKPHNEGGAGVTPTNAKWKHVESIFPLHSHSFNKEWIKKWSSKYTLEQTDIDNIRDKFGESVAFYFAFLRSYFRFLVIPSAFGFGAWLLLGQFSYLYALLCGLWSVVFFEYWKKQEVDLAVQWGVRGVSSIQQSRPEFEWEHEVKVYPPMKRVKTQLLQIPFALACVVALGALIVTCNSLEVFINFLPTIFLVIGTPTISGVLMGAAEKLNAMENYATVDAHDAALIQKQFVLNFMTSYMALFFTAFVYIPFGHPFLNFWRATAINPARISNQMFYFTVTAQIVNFATEVVVPYIKQQAFQKHEEEAEFLQRVREECTLEEYDVSGDYREMVMQFGYVAMFSVAWPLAACCFLVNNWVELRSDALKIAISSRRPIPWRTDSIGPWLTALSFLSWLGSITSSAIVYLCSKAWGLLLSILFAEHFYLVVQLAVRFVLSKLDQETIEIGRRMI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of closed groove scrambling by a TMEM16 protein.
pubmed doi rcsb
molecule keywords Lipid scramblase nhTMEM16
molecule tags Lipid transport
source organism Fusarium vanettenii 77-13-4
total genus 178
structure length 551
sequence length 697
chains with identical sequence B
ec nomenclature
pdb deposition date 2023-08-04
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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