8TPTA

Nhtmem16 a444p mutant in lipid nanodiscs with msp1e3 scaffold protein in the presence of ca2+ (long tm6/short tm6)
Total Genus 208
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
208
sequence length
700
structure length
579
Chain Sequence
SNFGVDFVIHYKVPAAERDEAEAGFVQLIRALTTVGLATEVRHGENESLLVFVKVSPDLFAKQVYRARLGDWLHGVRVEAERLRLIYLMITKPHNEGGAGVTPTNAKWKHVESIFPLHSHSFNKEWIKKWSSKYTLEQTDIDNIRDKFGESVAFYFAFLRSYFRFLVIPSAFGFGAWLLLGQFSYLYALLCGLWSVVFFEYWKKQEVDLAVQWGVRGVSSIQQSRPEFEWEHEAKVYPPMKRVKTQLLQIPFALACVVALGALIVTCNSLEVFINEVYSGPQYLGFLPTIFLVIGTPTISGVLMGAAEKLNAMENYATVDAHDAALIQKQFVLNFMTSYMALFFTAFVYIPFGHILHPFLNFWRINPARISNQMFYFTVTPQIVNFATEVVVPYIKQQAFEEAEFLQRVREECTLEEYDVSGDYREMVMQFGYVAMFSVAWPLAACCFLVNNWVELRSDALKIAISSRRPIPWRTDSIGPWLTALSFLSWLGSITSSAIVYLCSNAWGLLLSILFAEHFYLVVQLAVRFVLSKLPGLQKERKERFQTKKRLLTPEEMFWQRQRGMQETIEIGRRMIEQQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of closed groove scrambling by a TMEM16 protein.
pubmed doi rcsb
molecule keywords Lipid scramblase nhTMEM16
molecule tags Lipid transport
source organism Fusarium vanettenii 77-13-4
total genus 208
structure length 579
sequence length 700
chains with identical sequence B
ec nomenclature
pdb deposition date 2023-08-04
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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