8TV5C

Structure of the epha2 lbdcrd bound to fabs1ce_l1 in a 2:1 (epha2 to fab) ratio
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
301
structure length
294
Chain Sequence
KEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRMPCTL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Synthetic antibodies targeting EphA2 induce diverse signaling-competent clusters with differential activation.
pubmed doi rcsb
molecule keywords S1CE variant of Fab_L1 heavy chain
molecule tags Signaling protein/immune system
source organism Homo sapiens
total genus 40
structure length 294
sequence length 301
chains with identical sequence F
ec nomenclature ec 2.7.10.1: receptor protein-tyrosine kinase.
pdb deposition date 2023-08-17
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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